Characterization of leukemia-derived extracellular vesicles and subsequent effects on mesenchymal stem cell phenotype

      Exosomes are nanosized extracellular vesicles (EVs) released from cells and transferred to neighboring cells to induce changes via their RNA, DNA and protein cargo. Previous studies have suggested that leukemia-derived EVs contribute to cancer-promoting phenotypic alterations in bone marrow stromal cells. This study aims to understand the effects of leukemic-derived EVs on human mesenchymal stem cells (hMSCs).
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