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Phase II study of haploidentical stem cell transplantation using ex vivo photodepletion of donor lymphocyte infusions to eliminate anti-host reactivity results in low relapse rates and high survival rates: Final 2 year follow-up

      Introduction: T-cell depleted haploidentical hematopoietic stem cell transplantation (HSCT) often suffers from delayed immune reconstitution. To overcome this issue, we have developed a donor lymphocyte infusion (DLI) product (ATIR101) that uses ex vivo photodepletion to selectively prevent graft-versus-host disease, while preserving anti-infection and anti-leukemia activity.
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