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Development of a bioartificial oesophagus engineered with primary mesoangioblasts, neural and epithelial cells for preclinical studies

      A suitable oesophageal replacement is needed in several genetic and acquired conditions, such as long-gap oesophageal atresia or tumours and lesions. Oesophageal tissue engineering is an emerging therapeutic option aiming at developing functional tissue substitutes. Engineering the oesophageal layers is a key factor to restore functional properties of the tissue and to foster complete regeneration in vivo.
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