Background: Canine spinal injury is often associated with sudden impact injury such as being
hit by an automobile. Primary injuries to the spine can include cord laceration, spine
compression from ruptured disk or clot, spine concussion associated with vertebral
fracture or disk herniation, and lack of blood flow due to clot or emboli which can
occur independently or at the same time. The animal may exhibit paralysis and loss
of involuntary muscle activity. Such is the case of M001- a Siberian husky breed of
pet dog. The study aimed to validate the therapeutic effect of stem cell therapy using
adipose-derived mesenchymal stem cells (Ad-MSC), endothelial progenitor cells (EPC)
and neural progenitor cells (NPC) to a case of canine spinal injury.
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