Background: Canine spinal injury is often associated with sudden impact injury such as being hit by an automobile. Primary injuries to the spine can include cord laceration, spine compression from ruptured disk or clot, spine concussion associated with vertebral fracture or disk herniation, and lack of blood flow due to clot or emboli which can occur independently or at the same time. The animal may exhibit paralysis and loss of involuntary muscle activity. Such is the case of M001- a Siberian husky breed of pet dog. The study aimed to validate the therapeutic effect of stem cell therapy using adipose-derived mesenchymal stem cells (Ad-MSC), endothelial progenitor cells (EPC) and neural progenitor cells (NPC) to a case of canine spinal injury.
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