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Abstract| Volume 18, ISSUE 6, SUPPLEMENT , S13-S14, June 2016

Vaccination with Wilms' Tumor Antigen (WT1) mRNA-Electroporated Dendritic Cells as an Adjuvant Treatment in 60 Cancer Patients: Report of Clinical Effects and Increased Survival in Acute Myeloid Leukemia, Metastatic Breast Cancer, Glioblastoma and Mesothelioma

DOI:https://doi.org/10.1016/j.jcyt.2016.03.036
Vaccination with Wilms' Tumor Antigen (WT1) mRNA-Electroporated Dendritic Cells as an Adjuvant Treatment in 60 Cancer Patients: Report of Clinical Effects and Increased Survival in Acute Myeloid Leukemia, Metastatic Breast Cancer, Glioblastoma and Mesothelioma
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      We have previously reported the clinical and immunological effects of vaccination with dendritic cells electroporated with WT1 mRNA (WT1/DC) in 10 patients with acute myeloid leukemia (AML) (Van Tendeloo et al. PNAS 2010). In the present study, we expanded on the initial results and investigated WT1/DC as an adjuvant treatment in 60 high-risk cancer patients.
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      DOI: https://doi.org/10.1016/j.jcyt.2016.03.036

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