Background: RDEB is an inherited skin blistering disease caused by mutations in COL7A1 that encodes C7, a major component in anchoring fibrils at the basement membrane. We recently demonstrated that human cord blood (CB) derived unrestricted somatic stem cells promote wound healing and ameliorate blistering phenotype in Col7a1-/- (RDEB) mice. We also reported our experience in using HPDSCs as novel and universal donor cells to enhance CB engraftment and immune reconstitution in patients with malignant and non-malignant diseases.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Cytotherapy
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect