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Neuro-regenerative effect of autologous mesenchymal stem cell therapy in cerebral palsy patients: pilot clinical trial

      Stem cell-based therapies provide hope for various CNS diseases including perinatal hypoxic ischemic insults of the brain. Stem cells have the capacity to proliferate in culture, migrate and disseminate following implantation within the adult CNS. The neuroregenerative potential of bone marrow-derived mesenchymal stem cells (MSCs) is proposed to be through paracrine effect, stimulation of endogenous stem cells, angiogenesis, in addition to the disputed possibility of direct transdifferentiation.
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