MIF-CXCR4 as a novel axis for mesenchymal stem cell recruitment to tumors in vivo

      Figure thumbnail fx1
      MIF or CXCR4 knockdown impair MSC motility in a 3D spheroid model. MDAMB231 transfected with luciferase strawberry marker (LS) (top and bottom panels) or with MIFshRNAGFP (middle panel) were grown as spheroids. MSCs were transfected either with LS (middle panel) or transduced with CXCR4shRNA GFP (bottom panel) or non silencing (NS) GFP (top panel). The pictures are representative of the final scan from videos. Scale bars: 200mM.
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