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Human derived alternatives to fetal calf serum in cell culture

      Cell expansion for clinical applications is mainly performed in the presence of fetal calf serum (FCS). As FCS is known to cause disease transmission and incorporation of xenogenic proteins during cultivation, alternative supplements for cell culture media are desired. In recent years, human serum (huS) and human platelet lysate (hPL) turned out to be as potential or even better when used instead of FCS. We established production processes for huS and two different types of hPL in the last years. Now their efficacy in application as cell culture supplement should be determined.
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