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Autologous cultivated oral mucosal epithelial cells transplantation (COMET) with amniotic membrane based sheets for severe ocular chemical injury

      A normal ocular surface is covered with highly specialised corneal, limbal, and conjunctival epithelial cells that maintain surface integrity. Severe ocular surface damage caused by thermal and chemical burns represents a serious clinical challenge. Many attempts have been made to establish a surgical treatment for such diseases, including exploring the surgical treatment of epithelial transplantation with amniotic membrane (AM) as a base sheet to improve the outcome of ocular surface reconstruction. The aim of this study was to determine the feasibility of treating ocular burns with oral mucosal epithelial cells cultured onto AM.
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