Cytokines in cytotherapy

      One year since the merger of Cytotherapy with Cytokines, Cellular and Molecular Therapy, it is appropriate that the current issue of Cytotherapy includes no less than three papers focused on diagnostic and therapeutic aspects of biologic response modifiers in humans.
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        • Coley W.B.
        The treatment of inoperable sarcoma by bacterial toxins (the mixed toxins of the Streptococcus erysipelatis and the Bacillus prodigiosus).
        Proc R Soc Med. 1909; 3: 1
        • Old L.J.
        Tumor necrosis factor (TNF).
        Science. 1985; 230: 630-632
        • van Horssen R.
        • Ten Hagen T.L.
        • Eggermont A.M.
        TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility.
        Oncologist. 2006; 11: 397-408
        • Kishimoto T.
        Interleukin-6: from basic science to medicine: 40 years in immunology.
        Annu Rev Immunol. 2005; 23: 1-21
        • Trinchieri G.
        Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes.
        Blood. 1994; 84: 4008-4027
        • Lee C.K.
        • Gingrich R.D.
        • Hohl R.J.
        • Ajram K.A.
        Engraftment syndrome in autologous bone marrow and peripheral stem cell transplantation.
        Bone Marrow Transplant. 1995; 16: 175-182
        • Groeneveld A.B.
        • Bossink A.W.
        • van Mierlo G.J.
        • et al.
        Circulating inflammatory mediators in patients with fever: predicting bloodstream infection.
        Clin Diagn Lab Immunol. 2001; 8: 1189-1195